(S)-Tenofovir

(S)-Tenofovir is a medication used to treat HIV and HBV infections. It is a nucleotide reverse transcriptase inhibitor that works by inhibiting the activity of the reverse transcriptase enzyme, which is necessary for the replication of the viruses that cause these infections. The medication is available in different formulations, including oral tablets and topical gels. The oral tablets are typically taken once a day, with or without food, while the topical gel is applied to the affected area once a day. (S)-Tenofovir is metabolized in the liver and excreted through the kidneys. It has a half-life of approximately 17 hours, meaning that it stays in the body for a relatively long time. The medication is generally well-tolerated, with few side effects reported. However, some patients may experience mild to moderate gastrointestinal symptoms, such as diarrhea, nausea, and abdominal pain. The chemical structure of (S)-Tenofovir is similar to that of adenosine, a nucleotide found in DNA and RNA. The medication works by competing with adenosine for binding to the reverse transcriptase enzyme, thereby preventing the virus from copying its genetic material. (S)-Tenofovir is a potent medication that can effectively suppress the replication of HIV and HBV. However, it is not a cure for these infections and must be taken continuously to maintain viral suppression. It is important to follow the prescribed dosing regimen and to consult with a healthcare provider if any side effects or other concerns arise.