(3R,4S)-Tofacitinib
| Product Name | (3R,4S)-Tofacitinib |
|---|---|
| Alternate Names | Tofacitinib Impurities, Impurities of Tofacitinib |
| CAT No. | CS-T-62103 |
| CAS No. | 1092578-46-5 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 312.37 g/mol |
| Mol. For. | C₁₆H₂₀N₆O |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Tofacitinib |
| Purity | 95% |
| Therapeutic | Anti-Cancer / Oncology |
| Canonical Smiles | CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N |
| InchIKey | UJLAWZDWDVHWOW-AAEUAGOBSA-N |
| Inchl | InChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13-/m0/s1 |
| IUPAC | 3-[(3R,4S)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
(3R,4S)-Tofacitinib is a medication that belongs to a class of drugs known as Janus kinase inhibitors, or JAK inhibitors. It is used to treat various inflammatory diseases, including rheumatoid arthritis, psoriasis, and ulcerative colitis. The drug works by inhibiting the activity of Janus kinases, which play a crucial role in the immune response and inflammation.
Chemically, (3R,4S)-Tofacitinib is an organic compound with the molecular formula C16H20N6O. It is a white to off-white crystalline powder with a molecular weight of 312.37 g/mol. The drug is administered orally in tablet form, typically once or twice daily, depending on the condition being treated.
The pharmacokinetics of (3R,4S)-Tofacitinib are characterized by rapid absorption and distribution throughout the body. It is metabolized primarily in the liver and eliminated primarily in the feces. The drug has a half-life of approximately 3 hours, and steady-state concentrations are achieved after 5 days of dosing.
Overall, (3R,4S)-Tofacitinib is an effective treatment option for various inflammatory diseases, offering patients relief from painful symptoms and improving their quality of life. As with any medication, it is important to follow the prescribed dosing regimen and consult with a healthcare provider regarding any potential side effects or interactions with other medications.
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Related Compounds
N-(1-benzyl-4-methylpiperidin-3-yl)-N-methylnitrous amide | N-methyl-N-(4-methylpiperidin-3-yl)nitrous amide | N,4-dimethyl-1-nitrosopiperidin-3-amine | Tofacitinib impurity C | Tofacitinib Related Compound 29 | Tofacitinib Hydroxy Impurity | Tofacitinib impurity K | Tofacitinib Dihydro Impurity | Tofacitinib related compound 6 | Tofacitinib impurity Z | Tofacitinib impurity J | Tofacitinib Impurity (N-Des-(2-Cyanide-acetyl)-(3S,4R)) | N-methyl-N-(4-methylpyridin-3-yl)nitrous amide | Tofacitinib impurity P | Tofacitinib Nitroso Impurity 1 | Tofacitinib Impurity 6 | Tofacitinib Nitroso Impurity 5 | Tofacitinib N-Nitroso benzyl intermediate | Tofacitinib N-hydroxy impurity | Tofacitinib Nitroso Impurity 2 | Tofacitinib formyl impurity | Tofacitinib impurity N | TOFACITINIB IMPURITY TOF-IV | Tofacitinib Impurity 29 | Tofacitinib Dihydro Citricacid salt impurity | Tofacitinib Nitroso Impurity 4 | N-Nitroso Tofacitinib Amine Impurity | Tofacitinib N-oxide | Tofacitinib Impurity 36 | Tofacitinib Impurity 57 | Tofacitinib impurity V | Tofacitinib Diastereomer | Tofacitinib Nitroso Impurity 3 | Tofacitinib Nitroso Impurity | Tofacitinib impurity I | Tofacitinib- Keto Impurity | Tofacitinib N- acid Impurity | Tofacitinib Impurity 16 | Tofacitinib S,S Isomer | Tofacitinib Diastereomer-1 and 2 | N-methyl-N-(4-methyl-1-nitrosopiperidin-3-yl)nitrous amide | Tofacitinib Related Compound 26 HCl | Tofacitinib impurity T | Tofacitinib butyl ester impurity | Tofacitinib impurity G |