(3S,4R)-Tofacitinib
| Product Name | (3S,4R)-Tofacitinib |
|---|---|
| Alternate Names | Tofacitinib Impurities, Impurities of Tofacitinib |
| CAT No. | CS-T-62105 |
| CAS No. | 1092578-48-7 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 312.37 g/mol |
| Mol. For. | C₁₆H₂₀N₆O |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Tofacitinib |
| Purity | 95% |
| Therapeutic | Anti-Cancer / Oncology |
| Canonical Smiles | CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N |
| InchIKey | UJLAWZDWDVHWOW-DGCLKSJQSA-N |
| Inchl | InChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13-/m1/s1 |
| IUPAC | 3-[(3S,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
(3S,4R)-Tofacitinib is a medication used for the treatment of rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It is a Janus kinase (JAK) inhibitor that works by blocking the activity of JAK enzymes, which are involved in the signaling pathways that lead to inflammation in the body. By inhibiting JAK enzymes, (3S,4R)-Tofacitinib reduces inflammation and helps to alleviate the symptoms of these conditions.
(3S,4R)-Tofacitinib is a white to off-white crystalline powder that is soluble in water and has a molecular weight of 504.57 g/mol. Its chemical formula is C16H20N6O and its chemical name is (3S,4R)-N-methyl-3-(4-methyl-1H-imidazol-1-yl)-4-(2-(methylamino)pyrimidin-4-ylamino) cyclopent-1-ene-1-carboxamide.
It is important to note that (3S,4R)-Tofacitinib should not be used in patients with severe liver disease or a history of tuberculosis. Additionally, it may increase the risk of infection and malignancy, so patients taking this medication should be closely monitored for signs of infection or cancer.
In conclusion, (3S,4R)-Tofacitinib is a medication that is used to treat inflammatory conditions by inhibiting JAK enzymes. While it can be effective in alleviating symptoms, it is important to use this medication with caution and under the guidance of a healthcare professional.
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Related Compounds
Tofacitinib impurity G | N-methyl-N-(4-methylpiperidin-3-yl)nitrous amide | Tofacitinib Nitroso Impurity 4 | Tofacitinib S,S Isomer | Tofacitinib Related Compound 29 | Tofacitinib butyl ester impurity | Tofacitinib impurity Z | Tofacitinib Diastereomer-1 and 2 | Tofacitinib Nitroso Impurity | Tofacitinib impurity K | Tofacitinib N-oxide | N,4-dimethyl-1-nitrosopiperidin-3-amine | Tofacitinib Nitroso Impurity 1 | Tofacitinib impurity V | Tofacitinib Dihydro Citricacid salt impurity | Tofacitinib impurity I | Tofacitinib Impurity 29 | Tofacitinib Dihydro Impurity | Tofacitinib N-Nitroso benzyl intermediate | Tofacitinib impurity P | Tofacitinib impurity T | N-(1-benzyl-4-methylpiperidin-3-yl)-N-methylnitrous amide | N-methyl-N-(4-methyl-1-nitrosopiperidin-3-yl)nitrous amide | Tofacitinib Impurity 6 | Tofacitinib Nitroso Impurity 3 | Tofacitinib- Keto Impurity | N-Nitroso Tofacitinib Amine Impurity | Tofacitinib Impurity 16 | Tofacitinib formyl impurity | Tofacitinib related compound 6 | Tofacitinib Hydroxy Impurity | Tofacitinib impurity N | Tofacitinib impurity J | Tofacitinib Impurity 36 | Tofacitinib Nitroso Impurity 5 | Tofacitinib N- acid Impurity | Tofacitinib N-hydroxy impurity | Tofacitinib Related Compound 26 HCl | Tofacitinib Impurity (N-Des-(2-Cyanide-acetyl)-(3S,4R)) | TOFACITINIB IMPURITY TOF-IV | Tofacitinib impurity C | N-methyl-N-(4-methylpyridin-3-yl)nitrous amide | Tofacitinib Diastereomer | Tofacitinib Impurity 57 | Tofacitinib Nitroso Impurity 2 |