2’-Deoxy Cytidine-2’,2’-d2

2’-Deoxy Cytidine-2’,2’-d2, also known as 2’-Deoxycytidine-2’,2’-dideuterio, is a stable isotopologue of 2’-deoxycytidine. It is a modified form of the nucleoside cytidine, which is a component of RNA. This stable isotopologue is used in chemical and biochemical research as a tracer or internal standard in mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy experiments. The chemical formula of 2’-Deoxy Cytidine-2’,2’-d2 is C9H12D2N3O4. It is a deoxynucleoside, which means it is composed of a deoxyribose sugar and a nucleobase, in this case, cytosine. The deuterium atoms are located at the 2’ position of the sugar ring, making it a deuterium-labeled analogue of 2’-deoxycytidine. The usage of 2’-Deoxy Cytidine-2’,2’-d2 in research is primarily as an internal standard for liquid chromatography-mass spectrometry (LC-MS) and NMR analysis. It is utilized as a reference standard for the accurate quantitation of endogenous 2’-deoxycytidine in biological samples. It is also used as a tracer to study the metabolic pathways of nucleosides in cells and tissues. In conclusion, the stable isotopologue 2’-Deoxy Cytidine-2’,2’-d2 is an essential tool for chemical and biochemical research, particularly in mass spectrometry and NMR spectroscopy. Its unique chemical properties make it a valuable tracer and internal standard for studying nucleoside metabolism in biological systems.