0 0 Chemicalname=GLPG-1690,GLPG-1690,CAS=CAS=NAMolecular formula=C30H33FN8O2S | CLEARSYNTH

GLPG-1690

INHIBITORS

Product Details

CAT No.# CS-AV-00092
Category Inhibitors
CAS NA
Molecular Weight 588.7
Molecular Formula C30H33FN8O2S
Purity: >98
Synonyms: 2-((2-ethyl-6-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)piperazin-1-yl)-8-methylimidazo[1,2-a]pyridin-3-yl)(methyl)amino)-4-(4-fluorophenyl)thiazole-5-carbonitrile
Application Notes: NA
References: Desroy N, Housseman C, Bock X, Joncour A, Bienvenu N, Cherel L, Labeguere V, Rondet E, Peixoto C, Grassot JM, Picolet O, Annoot D, Triballeau N, Monjardet A, Wakselman E, Roncoroni V, Le Tallec S, Blanque R, Cottereaux C, Vandervoort N, Christophe T, Mollat P, Lamers M, Auberval M, Hrvacic B, Ralic J, Oste L, van der Aar E, Brys R, Heckmann B. Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methyli midazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation for the Treatment of Idiopathic Pulmonary Fibrosis. J Med Chem. 2017 May 1. doi: 10.1021/acs.jmedchem
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Product rating: 9 GLPG-1690 based on 20 ratings

  1. Inhibitors
  2. GLPG-1690

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5. Icatibant impurity 1
6. BISPHENOL AF (RING-13C12)
7. 0.1% TFA in Water ULC-MS
8. Metamizole EP Impurity C HCl
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10. Silodosin Metabolite
11. 2-Phenoxymethanesulfonanilide
12. Nimesulide EP Impurity A
13. Acetone HPLC
14. Crisaborole m-Isomer
15. Riluzole (1604337)
16. Pheniramine impurity B
17. Palbociclib N-Glucuronide
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19. Olmesartan N1-Trityl Impurity
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Smileys:
CCC(N=C1N2C=C(C=C1C)N3CCN(CC3)CC(N4CC(C4)O)=O)=C2N(C)C5=NC(C6=CC=C(C=C6)F)=C(S5)C#N



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