Fostriecin

METABOLITES

Product Details

CAT No.# CS-CM-00090
Category Metabolites
CAS 87810-56-8
Molecular Weight 430.38
Synonyms: (1E,7E,9E,11E)-3,6,13-trihydroxy-3-methyl-1-(6-oxo-3,6-dihydro-2H-pyran-2-yl)trideca-1,7,9,11-tetraen-4-yl dihydrogen phosphate
Application Notes: Fostriecin is the most fully characterised member of a family of phosphate esters of a triene antibiotic. The antitumor potential of fostriecin has attracted considerable interest, focused on its mode of action as a topoisomerase II inhibitor. Subsequent research has focused on this metabolite's selective inhibition of protein phosphatase PP2A.Chromosome condensation induced by fostriecin does not require p34cdc2 kinase activity and histone H1 hyperphosphorylation, but is associated with enhanced histone H2A and H3 phosphorylation.
COA / MSDS:    View COA    MSDS    Enquire
The balance used are calibrated with weights traceable to National Standards NIST for accuracy
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8. Icatibant impurity 1
9. BISPHENOL AF (RING-13C12)
10. 0.1% TFA in Water ULC-MS
11. Metamizole EP Impurity C HCl
12. Silodosin Metabolite D4
13. Brivaracetam Carboxylic acid metabolite [UCB 42145]
14. Terbuthylazine D5
15. tibolone (848)
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This page contains information about Fostriecin Cas 87810-56-8 and its Metabolites.
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