Ivermectin B1a
METABOLITES    
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CAT No. CS-CM-00111
Category Metabolites
Parent API Ivermectin
CAS 71827-03-7
Mol. Weight 875.09 g/mol
Mol. Formula C48H74O14
View COA View MSDS
Product Description
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Synonyms (1'R,2R,4'S,5S,6R,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-6-[(2S)-2-Butanyl]-21',24'-dihydroxy-12'-{[(2R,4S,5S,6S)-5-{[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-5,11',13',22'-tetramethyl-3,4,5,6-tetrahydro-2'H-spiro[pyran-2,6'-[3,7,19]trioxatetracyclo[15.6.1.14,8.020,24]pentacosa[10,14,16,22]tetraen]-2'-one; Dihydroavermectin B1a; 70161-11-4; 73910-57-3; 116522-39-5; 123022-60-6
Application Notes Ivermectin B1a (dihydroavermectin B1a) is the major component (>80%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamategated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectins and milbemycins are also potent insecticides. The individual 25-sec-butyl (B1a) and 25-iso-propyl (B1b) components of ivermectin have received little separate study.Avermectin/milbemycin resistance in trichostrongylid nematodes.
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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Related Results

- API Standards of Ivermectin
- Stable Isotopes of Ivermectin
- Metabolites of Ivermectin
- Impurities of Ivermectin
- Glucuronides of Ivermectin
- Intermediates of Ivermectin


Quality Assurance


c1
ISO 9001:2005
c4
OHSAS 18001:2007
c5
ISO 14001:2005
c4
ISO 17034:2016
c5
ISO/IEC 17025:2017
c5
NIST Calibrated