Piericidin A

METABOLITES

Product Details

CAT No.# CS-CM-00149
Category Metabolites
CAS 2738-64-9
Molecular Weight 415.56
Molecular Formula C25H37NO4
Synonyms: 2-((2E,5E,7E,9R,10R,11E)-10-hydroxy-3,7,9,11-tetramethyltrideca-2,5,7,11-tetraen-1-yl)-5,6-dimethoxy-3-methylpyridin-4(1H)-one
Application Notes: Piericidin A is the major analogue of a family of pyridyl antibiotics isolated from selected Streptomyces species. It is a specific, potent inhibitor of NADH-ubiquinone oxidoreductase (Complex I) that binds to ubiquinone binding site(s). Piericidin A inhibits both mitochondrial and bacterial NADH-ubiquinone oxidoreductases, binding close to NUODNUOB interfaceEvidence for a quinone binding site close to the interface between NUOD and NUOB subunits of Complex I. Prieur I. et al. Biochim.
References: Kroiss et al.., Nature Chemical Biology, 2010
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The balance used are calibrated with weights traceable to National Standards NIST for accuracy
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4. Lauroside D
5. Triazolam 13C D3
6. Icatibant impurity 1
7. BISPHENOL AF (RING-13C12)
8. 0.1% TFA in Water ULC-MS
9. Metamizole EP Impurity C HCl
10. Silodosin Metabolite D4
11. Brivaracetam Carboxylic acid metabolite [UCB 42145]
12. Terbuthylazine D5
13. tibolone (848)
14. (Z)-Dimethylvinphos
15. Silodosin Metabolite
16. 2-Phenoxymethanesulfonanilide
17. Nimesulide EP Impurity A
18. Acetone HPLC
19. Nandrolone Decanoate EP impurity F
20. N-(4-Bromophenyl)-3-methyl-N-(m-tolyl)aniline




This page contains information about Piericidin A Cas 2738-64-9 and its Metabolites.
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