Validamycin A

METABOLITES

Product Details

CAT No.# CS-CM-00183
Category Metabolites
CAS 37248-47-8
Molecular Weight 497.49
Molecular Formula C20H35NO13
Stock Status: In-Stock
Synonyms: (2R,3R,4S,5S,6R)-2-(((1R,2R,3S,4S,6R)-2,3-dihydroxy-6-(hydroxymethyl)-4-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)cyclohexyl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Application Notes: Validamycin A is the major analogue of a family of cyclitol disaccharides isolated from Streptomyces hygroscopicus var. limoneus by researchers at Takeda in 1970. Although commonly regarded as an aminoglycoside, validamycin shares little in common with conventional aminoglycosides such as streptomycin and gentamicin. Validamycin A is a potent antifungal agent and is used to control fungi in crop production. Validamycin A acts as a potent inhibitor of trehalase, an important enzyme in carbohydrate storage and ultilisation in fungi.Studies on validamycins, new antibiotics. I. Streptomyces hygroscopicus var. limoneus nov. var. validamycin - producing organism.
References: Duncan J. Wardrop and Samanthi L. Waidyarachchi. , Nat. Prod. Rep., 2010, 27, 1431.
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The balance used are calibrated with weights traceable to National Standards NIST for accuracy
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4. Lauroside D
5. Triazolam 13C D3
6. Icatibant impurity 1
7. BISPHENOL AF (RING-13C12)
8. 0.1% TFA in Water ULC-MS
9. Metamizole EP Impurity C HCl
10. Silodosin Metabolite D4
11. Brivaracetam Carboxylic acid metabolite [UCB 42145]
12. Terbuthylazine D5
13. tibolone (848)
14. (Z)-Dimethylvinphos
15. Silodosin Metabolite
16. 2-Phenoxymethanesulfonanilide
17. Nimesulide EP Impurity A
18. Acetone HPLC
19. Nandrolone Decanoate EP impurity F
20. N-(4-Bromophenyl)-3-methyl-N-(m-tolyl)aniline


Smileys:
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This page contains information about Validamycin A Cas 37248-47-8 and its Metabolites.
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