Validamycin A
Availability: In-Stock
Dispatch by : 19-Nov-2019 5:00 PM
CAT No. CS-CM-00183
Category Metabolites
Parent API Validamycin
CAS 37248-47-8
Mol. Weight 497.49 mol/g
Mol. Formula C20H35NO13
Product Description
Stock Status In-Stock
Dispatch by : 19-Nov-2019 5:00 PM
Synonyms (2R,3R,4S,5S,6R)-2-(((1R,2R,3S,4S,6R)-2,3-dihydroxy-6-(hydroxymethyl)-4-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)cyclohexyl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Application Notes Validamycin A is the major analogue of a family of cyclitol disaccharides isolated from Streptomyces hygroscopicus var. limoneus by researchers at Takeda in 1970. Although commonly regarded as an aminoglycoside, validamycin shares little in common with conventional aminoglycosides such as streptomycin and gentamicin. Validamycin A is a potent antifungal agent and is used to control fungi in crop production. Validamycin A acts as a potent inhibitor of trehalase, an important enzyme in carbohydrate storage and ultilisation in fungi.Studies on validamycins, new antibiotics. I. Streptomyces hygroscopicus var. limoneus nov. var. validamycin - producing organism.
References Duncan J. Wardrop and Samanthi L. Waidyarachchi. , Nat. Prod. Rep., 2010, 27, 1431.
Smileys O[C@H]1[C@@H]([C@H](C[C@H](N[C@@]([C@@H]([C@@H](O)[C@@H]2O)O)([H])C=C2CO)[C@@H]1O)CO)O[C@]([C@@H]([C@@H](O)[C@@H]3O)O)([H])O[C@@H]3CO
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The balance used are calibrated with weights Traceable to National Standards NIST for accuracy

Quality Assurance

ISO 9001:2005
OHSAS 18001:2007
ISO 14001:2005
NIST Calibrated
Related Results

- API Standards of Validamycin
- Stable Isotopes of Validamycin
- Metabolites of Validamycin
- Impurities of Validamycin
- Glucuronides of Validamycin
- Intermediates of Validamycin

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