SCH 442416, Desmethyl
INHIBITORS    
Availability: Available - Dispatch by : 22-Dec-2019 5:00 PM
CAT No. CS-CM-00315
Category Inhibitors
CAS 188112-92-7
Mol. Weight 375.38 g/mol
Mol. Formula C19H17N7O2
View COA View MSDS
Product Description
Stock Status Available - Dispatch by : 22-Dec-2019 5:00 PM
Synonyms 4-(3-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)propyl)phenol
Application Notes Precursor for [11C]SCH442416 for PET studies; Radioligand precursor of the highly selective and potent A2A adenosine receptor antagonist SCH 442416 (Axon 1264). Desmethyl SCH 442416 is less potent and less selective in binding the A2A receptor than SCH 445416 (Ki values 44 nM, 48 nM, and 34 nM for A1, A2A and A3 respectively).
References T. Santhosh Kumar et al.,Molecular Recognition Section
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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