SCH 442416, Desmethyl
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CAT No. CS-CM-00315
Category Inhibitors
CAS 188112-92-7
Mol. Weight 375.38 g/mol
Mol. Formula C19H17N7O2
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Product Description
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Synonyms 4-(3-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)propyl)phenol
Application Notes Precursor for [11C]SCH442416 for PET studies; Radioligand precursor of the highly selective and potent A2A adenosine receptor antagonist SCH 442416 (Axon 1264). Desmethyl SCH 442416 is less potent and less selective in binding the A2A receptor than SCH 445416 (Ki values 44 nM, 48 nM, and 34 nM for A1, A2A and A3 respectively).
References T. Santhosh Kumar et al.,Molecular Recognition Section
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy

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NIST Calibrated