EMA400
INHIBITORS    
Availability: Available - Dispatch by : 21-Dec-2019 5:00 PM
CAT No. CS-O-16982
Category Inhibitors
CAS 152362-51-1
Mol. Weight 507.59 g/mol
Mol. Formula C32H29NO5
View COA View MSDS
Product Description
Stock Status Available - Dispatch by : 21-Dec-2019 5:00 PM
Synonyms EMA400; EMA 400; EMA-400; PD-126055; PD126055; PD 126055; 5-Benzyloxy-2-diphenylacetyl-6-methoxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid
Purity (%) >98
Solubility Soluble in DMSO
Appearance Solid powder
References Rice AS, Smith MT. Angiotensin II type 2-receptor: new clinically validated target in the treatment of neuropathic pain. Clin Pharmacol Ther. 2015 Feb;97(2):128-30. doi: 10.1002/cpt.29. Epub 2014 Dec 20. PubMed PMID: 25670516. McCarthy T. Development of EMA401 as an orally-administered, highly-selective angiotensin II type 2 receptor antagonist for the treatment of neuropathic pain. J Peripher Nerv Syst. 2014 Oct;19 Suppl 2:S13-4. doi: 10.1111/jns.12080_4. Review. PubMed PMID: 25269730.
Pubchem Id 9892451
Smiles COC1=C(C2=C(CN(C(C2)C(=O)O)C(=O)C(C3=CC=CC=C3)C4=CC=CC=C4)C=C1)OCC5=CC=CC=C5
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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c1
ISO 9001:2005
c4
OHSAS 18001:2007
c5
ISO 14001:2005
c5
NIST Calibrated


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