Cercosporamide

INHIBITORS

   
Cercosporamide belongs to the category of Inhibitors with CAS Registry No: 131436-22-1

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CAT No. CS-T-10938
Category Inhibitors
CAS 131436-22-1
Mol. Weight 331.28 g/mol
Mol. Formula C16H13NO7
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More info about Cercosporamide
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Synonyms (9aS)-xy-9a-methyl-9-oxo-4-dibenzofurancarboxamide
Purity (%) >98%
Application Notes Cercosporamide is a potent inhibitor of MAP-kinase interacting kinase-2 (Mnk2) and JAK3. Cercosporamide effectively inhibits eIF4E phosphorylation as well as inibitiing inhibits Pkc1. Cercosporamide displays antiproliferative and proapoptotic activity in cancer cells in vitro.
References Sussman, A. et al.: Eukaryot. Cell, 3, 932 (2004); Konicek, B.W. et al.: Cancer Res., 71, 1849 (2011); Hou, J. et al.: Oncotarget, 3, 118 (2012);
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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