5-Hydroxy Omeprazole
METABOLITES    
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CAT No. CS-T-27949
Category Metabolites
Parent API Omeprazole
CAS 92340-57-3
Mol. Weight 361.42 g/mol
Mol. Formula C17H19N3O4S
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Product Description
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Synonyms Hydroxyomeprazole; (4-methoxy-6-{[(6-methoxy-1h-benzimidazol-2-yl)sulfinyl]methyl}-5-methylpyridin-3-yl)methanol; 5-Methoxy-2-(((4-methoxy-3-methyl-5-hydroxymethyl-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole; 92340-57-3; 5'-Hydroxyomeprazole; 5-Hydroxymethylomeprazole;
Purity (%) >98%
Application Notes 5-Hydroxy Omeprazole is the main metabolite of Omeprazole , which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.
References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)
Smiles CC1=C(C(=CN=C1CS(=O)C2=NC3=C(N2)C=C(C=C3)OC)CO)OC
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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Related Results

- API Standards of Omeprazole
- Stable Isotopes of Omeprazole
- Metabolites of Omeprazole
- Impurities of Omeprazole
- Glucuronides of Omeprazole
- Intermediates of Omeprazole


Quality Assurance


c1
ISO 9001:2005
c4
OHSAS 18001:2007
c5
ISO 14001:2005
c4
ISO 17034:2016
c5
ISO/IEC 17025:2017
c5
NIST Calibrated