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CAT No. CS-T-38767
Category Agonists
CAS 169528-11-4
Mol. Weight 798.07 g/mol
Mol. Formula C42H71N9O6
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Product Description
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Synonyms ethyl 2-(2-(2-(1-(6-amino-2-((2,6-diaminohexyl)amino)hexanoyl)pyrrolidine-2-carboxamido)-3-(1H-indol-3-yl)propanamido)-3,3-dimethylbutanamido)-4-methylpentanoate
Purity (%) >98%
Application Notes PD 149163 is a selective, brain penetrating Neurotensin NTR1 receptor agonist. Neurotensin agonists such as PD 149163 block the prepulse inhibition deficits produced by a 5-HT2A and an a1 agonist. As a result, PD 149163 shows pro-cognitive, antipsychotic and anxiolytic effects.
References Feifel, D. et al.: Neuropsychophamacology, 28, 651 (2003); Shilling, P.D. et al.: Psychopharmacolgy, 175, 353 (2004);
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy

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NIST Calibrated