RTI-336
INHIBITORS    
Availability: Available - Dispatch by : 23-Dec-2019 5:00 PM
CAT No. CS-T-42007
Category Inhibitors
CAS 204069-50-1
Mol. Weight 429.39 g/mol
Mol. Formula C24H26Cl2N2O
View COA View MSDS
Product Description
Stock Status Available - Dispatch by : 23-Dec-2019 5:00 PM
Synonyms (1R,2S,3S,5S)-3-thylphenyl)-5-isoxazolyl]-8-azne Hydrochloride;5-(3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl)-3-(p-tolyl)isoxazole hydrochloride
Purity (%) >98%
Application Notes RTI-336 is a a phenyltropane cocaine analog that acts selective dopamine reuptake inhibitor. RTI-336 binds to the dopamine transporter with around 20 times the affinity of cocaine but produces relatively mild stimulant effects. RTI-336 is a potential candidate for pharmacotherapy for treating cocaine addiction.
References Carroll, F.I. et al.: AAPS J., 8, E196 (2006); Czoty, P.W. et al.: Pharmacol. Biochem. Behav., 96, 274 (2010); Carroll, F. et al.: Eur. J. Pharmacol., 553, 149 (2006);
Pubchem Id 11524766
Smiles CC1=CC=C(C=C1)C2=NOC(=C2)C3C4CCC(N4C)CC3C5=CC=C(C=C5)Cl.Cl
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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c1
ISO 9001:2005
c4
OHSAS 18001:2007
c5
ISO 14001:2005
c5
NIST Calibrated


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