5-(Trifluoromethyl)-2-(chloromethyl)-1,3,4-oxadiazole

INTERMEDIATES

   
5-(Trifluoromethyl)-2-(chloromethyl)-1,3,4-oxadiazole is a Intermediate of Sitagliptin with CAS Registry No: 723286-98-4
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CAT No. CS-T-45317
Category Intermediates
Parent API Sitagliptin
CAS 723286-98-4
Mol. Weight 186.52 g/mol
Mol. Formula C4H2ClF3N2O
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More info about 5-(Trifluoromethyl)-2-(chloromethyl)-1,3,4-oxadiazole
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Synonyms 2-Chloromethyl-5-trifluoromethyl-1,3,4-oxadiazole
Storage Conditions For long term store at -20°C, Under Inert Atmosphere
Purity (%) >98%
Solubility Chloroform, Dichloromethane, Ethyl Acetate, Methanol
Appearance Brown Oil
Application Notes Sitagliptin intermediate. An anti-hypertensive agent for the treatment of diabetes and hypertension.
References Kim, D., et al.: J. Med. Chem., 48, 141 (2005), Ahren, B., et al.: Eur. J. Pharmacol., 521 164 (2005),
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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