Dabrafenib D9 | CAS 1423119-98-5 | Stable Isotopes

Dabrafenib D9

Dabrafenib D9
CAT No. CS-T-51570
Category Stable Isotopes
Parent API Dabrafenib
CAS 1423119-98-5
Purity (%) >98%
Application Dabrafenib-d9 is the isotope labelled analog of Dabrafenib ; an inhibitor of mutated BRAF kinase. Dabrafenib also has clinical activity with a manageable safety profile in clinical trials of phase 1 and 2 in patients with BRAF(V600)-mutated metastatic melanoma.
References Hauschild, A., et al.: Lancet, 380, 358 (2012); Falchook, G.S., et al.: Lancet, 379, 1893 (2012); Ascierto, P.A., et al.: J. Clin. Oncol., 31, 3205 (2013)
Mol. Weight 528.62 g/mol
Formula C23H11D9F3N5O2S2
Stock Status For Exact delivery date, please contact sales@clearsynth.com
Synonyms N-[3-[5-(2-Amino-4-pyrimidinyl)-2-[1,1-di(methyl-d3)ethyl-2,2,2-d3]-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro-benzenesulfonamide; GSK 2118436-d9; Tafinlar-d9.
Documents COA   MSDS

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