Demecolcine Hydrobromide Salt
API STANDARDS    
Availability: Compound under re-stock / certification. Please enquire for exact delivery date
CAT No. CS-T-51836
Category API Standards
Parent API Demecolcine
CAS 1246817-95-7
Mol. Weight 452.34 g/mol
Mol. Formula C21H26BrNO5
View COA View MSDS
Product Description
Stock Status Compound under re-stock / certification. Please enquire for exact delivery date
Synonyms (10S)-3,4,5,14-tetramethoxy-10- (methylamino)2,4,6,11,14-hexaen-13-one hydrobromide
Storage Conditions For long term store at -20°C
Purity (%) >98%
Melting Point (℃)224-229 
Solubility Dichloromethane, DMSO, Methanol
Appearance Pale Yellow Solid
Application Notes An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
References Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev
Pubchem Id 71315175
Smiles CNC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC.Br
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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Related Results

- API Standards of Demecolcine
- Stable Isotopes of Demecolcine
- Metabolites of Demecolcine
- Impurities of Demecolcine
- Glucuronides of Demecolcine
- Intermediates of Demecolcine

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