N-(2-Hydroxyethyl)-11-azaartemisinin

IMPURITIES

Product Details

CAT No.# CS-T-56006
Category Impurities
CAS 255731-00-1
Molecular Weight 325.4
Molecular Formula C17H27NO5
Purity: >98%
Synonyms: (3R,5aS,6R,8aS,9R,12R,12aR)-Decahydro-11-(2-hydroxyethyl)-3,6,9-trimethyl-3,12-epoxy-1,2-dioxepino[4,3-i]isoquinolin-10(3H)-one.
Application Notes: A derivative of 11-Azaartemisinin which showed a high order of activity against multidrug-resistant malaria by oral route.
References: Meshnick, S.R., et al.: Microbiol. Rev., 60, 301 (1996), O’Neill, P.M., et al.: J. Med. Chem., 45, 1052 (2002), Rottmann, M., et al.: J. Med. Chem., 51, 1035 (2008),
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The balance used are calibrated with weights traceable to National Standards NIST for accuracy
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9. 0.1% TFA in Water ULC-MS
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