25-Hydroxy-cholesterol 3-Sulfate Ester Sodium Salt
IMPURITIES    
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CAT No. CS-T-78822
Category Impurities
CAS 1174047-40-5
Mol. Weight 504.7 g/mol
Mol. Formula C27H45NaO5S
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Product Description
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Synonyms Sodium (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl Sulfate
Application Notes 25-Hydroxy-cholesterol 3-Sulfate Ester is a derivative of 4-Hydroxy Cholesterol, a metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.
Smiles O=S(O[C@H]1CC[C@]2(C)[C@@]3([H])CC[C@]4(C)[C@@H]([C@@H](CCCC(C)(O)C)C)CC[C@@]4([H])[C@]3([H])CC=C2C1)([O-])=O.[Na+]
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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c1
ISO 9001:2005
c4
OHSAS 18001:2007
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ISO 14001:2005
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ISO 17034:2016
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ISO/IEC 17025:2017
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NIST Calibrated