Pregnenolone Carbonitrile
Availability: This product can be dispatched by 7-Mar-2020
CAT No. CS-T-84729
Category Steroids
CAS 1434-54-4
Mol. Weight 341.49 g/mol
Mol. Formula C22H31NO2
View COA View MSDS
Product Description
Stock Status This product can be dispatched by 7-Mar-2020
Synonyms 3β-Hydroxy-20-oxo-pregn-5-ene-16α-carbonitrile; 16α-Cyanopregnenolone; 3β-Hydroxy-20-oxo-5-pregnen-16α-carbonitrile; 3β-Hydroxy-20-oxopregn-5-ene-16α-carbonitrile; 5-Pregnen-3β-ol-20-one-16α-carbonitrile; PCN; Pregn-5-ene-3β-ol-20-oxo-16α-carbonitrile;
Storage Conditions Hygroscopic, -20?C Freezer, Under inert atmosphere
Melting Point (℃)221-224C 
Solubility DMSO (Slightly), Methanol (Slightly, Heated)
Appearance Off-White to Pale Beige Solid
Application Notes Pregnenolone Carbonitrile is a glucocorticoid receptor antagonist that induces the expression of the CYP3A family of steroid hydroxylases and modulates sterol and bile acid biosynthesis in vivo. Pregnenolone Carbonitrile is an an activator of rat pregnane X receptor (PXR).
Smiles O[[email protected]]1CC[[email protected]]2(C)[[email protected]@]3([H])CC[[email protected]]4(C)[[email protected]@H](C(C)=O)[[email protected]](C#N)C[[email protected]@]4([H])[[email protected]]3([H])CC=C2C1
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy

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