Amlodipine D4
| Product Name | Amlodipine D4 |
|---|---|
| Alternate Names | Amlodipine Stable Isotopes, Stable Isotopes of Amlodipine |
| CAT No. | CS-CX-00109 |
| CAS No. | 1185246-14-3 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 412.90 g/mol |
| Mol. For. | C₂₀H₂₁D₄ClN₂O₅ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Amlodipine |
| Smileys | CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN |
| Canonical Smiles | CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN |
| InchIKey | HTIQEAQVCYTUBX-YQUBHJMPSA-N |
| Inchl | InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3/i9D2,10D2 |
| IUPAC | 3-O-ethyl 5-O-methyl 2-[(2-amino-1,1,2,2-tetradeuterioethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Amlodipine D4 is a deuterated form of amlodipine, a commonly used medication for the treatment of hypertension and angina. Amlodipine D4 has the same chemical structure as amlodipine, but with four deuterium atoms replacing four hydrogen atoms. This modification is done for research purposes, as it allows for more accurate analysis of drug metabolism and pharmacokinetics.
Amlodipine D4 works by inhibiting the influx of calcium ions into smooth muscle cells, leading to vasodilation and relaxation of the blood vessels. This results in a decrease in blood pressure and improved blood flow to the heart. Amlodipine D4 has a long half-life of approximately 30-50 hours, allowing for once-daily dosing.
Amlodipine D4 is typically administered orally in tablet form and is available in various strengths. The dosing regimen will depend on the patient's age, medical history, and the severity of their condition. Amlodipine D4 is generally well-tolerated, with common side effects including dizziness, headache, and swelling in the ankles and feet.
In conclusion, Amlodipine D4 is a deuterated form of amlodipine that is used for research purposes to better understand the pharmacokinetics and metabolism of the drug. It works by inhibiting calcium influx, leading to vasodilation and a decrease in blood pressure. Amlodipine D4 is typically administered orally and is well-tolerated, with common side effects including dizziness and headache.
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Related Compounds
Amlodipine 13C6 | Amlodipine D4 Maleate | R-Amlodipine D4 | Amlodipine benzenesulfonate 13C6 | N-Nitroso Amlodipine D4 | S-Amlodipine Besylate-D4 | Amlodipine benzenesulfonate, racemic mixture 13C | Amlodipine 13C4 | Amlodipine benzenesulfonate D3 | S-Amlodipine D4 |