Amlodipine D4

Product Name Amlodipine D4
Alternate Names Amlodipine Stable Isotopes, Stable Isotopes of Amlodipine
CAT No. CS-CX-00109
CAS No. 1185246-14-3
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 412.90 g/mol
Mol. For. C₂₀H₂₁D₄ClN₂O₅
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Amlodipine
Smileys CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN
Canonical Smiles CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN
InchIKey HTIQEAQVCYTUBX-YQUBHJMPSA-N
Inchl InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3/i9D2,10D2
IUPAC 3-O-ethyl 5-O-methyl 2-[(2-amino-1,1,2,2-tetradeuterioethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Controlled No
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Size Price Quantity
5 MG $  209.00
$ 220.00
50 MG $  1,577.00
$ 1,660.00

What is the usage and chemical information of Amlodipine D4 ?


Amlodipine D4 is a deuterated form of amlodipine, a commonly used medication for the treatment of hypertension and angina. Amlodipine D4 has the same chemical structure as amlodipine, but with four deuterium atoms replacing four hydrogen atoms. This modification is done for research purposes, as it allows for more accurate analysis of drug metabolism and pharmacokinetics. Amlodipine D4 works by inhibiting the influx of calcium ions into smooth muscle cells, leading to vasodilation and relaxation of the blood vessels. This results in a decrease in blood pressure and improved blood flow to the heart. Amlodipine D4 has a long half-life of approximately 30-50 hours, allowing for once-daily dosing. Amlodipine D4 is typically administered orally in tablet form and is available in various strengths. The dosing regimen will depend on the patient's age, medical history, and the severity of their condition. Amlodipine D4 is generally well-tolerated, with common side effects including dizziness, headache, and swelling in the ankles and feet. In conclusion, Amlodipine D4 is a deuterated form of amlodipine that is used for research purposes to better understand the pharmacokinetics and metabolism of the drug. It works by inhibiting calcium influx, leading to vasodilation and a decrease in blood pressure. Amlodipine D4 is typically administered orally and is well-tolerated, with common side effects including dizziness and headache.

Related Compounds

S-Amlodipine Besylate-D4 | Amlodipine benzenesulfonate, racemic mixture 13C | N-Nitroso Amlodipine D4 | Amlodipine D4 Maleate | Amlodipine benzenesulfonate D3 | S-Amlodipine D4 | Amlodipine benzenesulfonate 13C6 | Amlodipine 13C4 | Amlodipine 13C6 | R-Amlodipine D4 |

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