S-Amlodipine D4

Product Name S-Amlodipine D4
Alternate Names Amlodipine Stable Isotopes, Stable Isotopes of Amlodipine
CAT No. CS-O-06405
CAS No. 1346617-19-3
Category Stable Isotopes
Stock Enquire
Mol. Wt. 412.90 g/mol
Mol. For. C₂₀H₂₁D₄ClN₂O₅
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Amlodipine
Purity 95%
Therapeutic Anti-Cancer / Oncology
Smileys O=C(C([C@@H](C(C=CC=C1)=C1Cl)C(C(OC)=O)=C(C)N2)=C2COC([2H])([2H])C([2H])([2H])N)OCC
Controlled No
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S-Amlodipine D4 is a deuterated version of S-amlodipine, a calcium channel blocker used to treat high blood pressure and chest pain caused by angina. The deuterium substitution at the four positions of the molecule enhances its stability and efficacy, leading to a longer half-life and improved pharmacokinetic properties. The mechanism of action of S-amlodipine D4 involves the inhibition of L-type calcium channels in the smooth muscle cells of the blood vessels, leading to relaxation and vasodilation. This results in the reduction of blood pressure and the improvement of blood flow to the heart, reducing the risk of heart attack and stroke. S-amlodipine D4 is typically administered orally in the form of a tablet, with a recommended dosage of 5 to 10 mg per day. It is important to follow the instructions provided by a healthcare professional and to not exceed the recommended dose. The chemical formula of S-amlodipine D4 is C20H23D4ClN2O5, with a molecular weight of 422.97 g/mol. It belongs to the dihydropyridine class of calcium channel blockers and is a white to off-white crystalline powder. S-amlodipine D4 is stable under normal conditions and is compatible with a range of excipients used in pharmaceutical formulations. Overall, S-amlodipine D4 is a highly effective and safe medication for the treatment of hypertension and angina, with improved pharmacokinetic properties due to its deuterium substitution.

Related Compounds

Amlodipine benzenesulfonate 13C6 | Amlodipine 13C4 | Amlodipine 13C6 | R-Amlodipine D4 | Amlodipine D4 Maleate | Amlodipine benzenesulfonate D3 | Amlodipine benzenesulfonate, racemic mixture 13C | S-Amlodipine Besylate-D4 | Amlodipine D4 | N-Nitroso Amlodipine D4 |

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