Amphotericin B-13C6 Methyl Ester

Product Name Amphotericin B-13C6 Methyl Ester
Alternate Names Amphotericin B Stable Isotopes, Stable Isotopes of Amphotericin B
CAT No. CS-O-13557
CAS No. 36148-89-7 (Unlabeled)
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Amphotericin B
Therapeutic Anti-Fungals
Smileys O=C([C@H]1[C@@](C[C@H](/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC2=O)O[13C@@](O[13C@H]([13CH3])[13C@@H](O)[13C@@H]3N)([H])[13C@H]3O)([H])O[C@](O)(C[C@H](C[C@H]([C@@H](CC[C@H](C[C@H](C2)O)O)O)O)O)C[C@@H]1O)OC
Inchl InChI=1S/C48H75NO17/c1-28-18-16-14-12-10-8-6-7-9-11-13-15-17-19-35(65-47-45(59)42(49)44(58)31(4)64-47)25-39-41(46(60)62-5)38(55)27-48(61,66-39)26-34(52)23-37(54)36(53)21-20-32(50)22-33(51)24-40(56)63-30(3)29(2)43(28)57/h6-19,28-39,41-45,47,50-55,57-59,61H,20-27,49H2,1-5H3/b7-6+,10-8+,11-9+,14-12+,15-13+,18-16+,19-17+/t28-,29-,30-,31+,32+,33+,34-,35-,36+,37+,38-,39-,41+,42-,43+,44+,45-,47-,48+/m0/s1
IUPAC methyl (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate
Controlled No
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Amphotericin B-13C6 Methyl Ester is a derivative of Amphotericin B, a polyene macrolide antibiotic produced by Streptomyces nodosus. It is known for its broad-spectrum antifungal activity and is used to treat severe systemic fungal infections. The methyl ester derivative is a stable form of the molecule that can be used in research and drug development. The chemical structure of Amphotericin B-13C6 Methyl Ester is similar to that of Amphotericin B, with the addition of six carbon-13 isotopes. This makes it useful for tracking the molecule in biological systems using mass spectrometry. The methyl ester group also improves the solubility of the molecule in organic solvents, making it easier to work with in the laboratory. In terms of usage, Amphotericin B-13C6 Methyl Ester can be used to study the pharmacokinetics and pharmacodynamics of Amphotericin B in animal models and in vitro systems. It can also be used to develop new formulations of Amphotericin B that improve its efficacy and reduce its toxicity. The methyl ester derivative has been shown to have similar antifungal activity to Amphotericin B, making it a valuable tool for understanding the mechanism of action of the drug. Overall, Amphotericin B-13C6 Methyl Ester is a useful molecule for researchers studying antifungal drugs and their pharmacology. Its stability and solubility make it a valuable tool for drug development and understanding the biological effects of Amphotericin B.

Related Compounds

Amphotericin B 13C6 | Amphotericin B Methyl Ester 13CD3 | Amphotericin B Methyl Ester D3 |

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