Amphotericin B-13C6 Methyl Ester
| Product Name | Amphotericin B-13C6 Methyl Ester |
|---|---|
| Alternate Names | Amphotericin B Stable Isotopes, Stable Isotopes of Amphotericin B |
| CAT No. | CS-O-13557 |
| CAS No. | 36148-89-7 (Unlabeled) |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Amphotericin B |
| Therapeutic | Anti-Fungals |
| Smileys | O=C([C@H]1[C@@](C[C@H](/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC2=O)O[13C@@](O[13C@H]([13CH3])[13C@@H](O)[13C@@H]3N)([H])[13C@H]3O)([H])O[C@](O)(C[C@H](C[C@H]([C@@H](CC[C@H](C[C@H](C2)O)O)O)O)O)C[C@@H]1O)OC |
| Canonical Smiles | CC1C=CC=CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)OC)OC3C(C(C(C(O3)C)O)N)O |
| InchIKey | UAZIZEMIKKIBCA-TYVGYKFWSA-N |
| Inchl | InChI=1S/C48H75NO17/c1-28-18-16-14-12-10-8-6-7-9-11-13-15-17-19-35(65-47-45(59)42(49)44(58)31(4)64-47)25-39-41(46(60)62-5)38(55)27-48(61,66-39)26-34(52)23-37(54)36(53)21-20-32(50)22-33(51)24-40(56)63-30(3)29(2)43(28)57/h6-19,28-39,41-45,47,50-55,57-59,61H,20-27,49H2,1-5H3/b7-6+,10-8+,11-9+,14-12+,15-13+,18-16+,19-17+/t28-,29-,30-,31+,32+,33+,34-,35-,36+,37+,38-,39-,41+,42-,43+,44+,45-,47-,48+/m0/s1 |
| IUPAC | methyl (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Amphotericin B-13C6 Methyl Ester is a derivative of Amphotericin B, a polyene macrolide antibiotic produced by Streptomyces nodosus. It is known for its broad-spectrum antifungal activity and is used to treat severe systemic fungal infections. The methyl ester derivative is a stable form of the molecule that can be used in research and drug development.
The chemical structure of Amphotericin B-13C6 Methyl Ester is similar to that of Amphotericin B, with the addition of six carbon-13 isotopes. This makes it useful for tracking the molecule in biological systems using mass spectrometry. The methyl ester group also improves the solubility of the molecule in organic solvents, making it easier to work with in the laboratory.
In terms of usage, Amphotericin B-13C6 Methyl Ester can be used to study the pharmacokinetics and pharmacodynamics of Amphotericin B in animal models and in vitro systems. It can also be used to develop new formulations of Amphotericin B that improve its efficacy and reduce its toxicity. The methyl ester derivative has been shown to have similar antifungal activity to Amphotericin B, making it a valuable tool for understanding the mechanism of action of the drug.
Overall, Amphotericin B-13C6 Methyl Ester is a useful molecule for researchers studying antifungal drugs and their pharmacology. Its stability and solubility make it a valuable tool for drug development and understanding the biological effects of Amphotericin B.
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Related Compounds
Amphotericin B Methyl Ester D3 | Amphotericin B 13C6 | Amphotericin B Methyl Ester 13CD3 |