des-(Glu13)-Bivalirudin
| Product Name | des-(Glu13)-Bivalirudin |
|---|---|
| Alternate Names | Bivalirudin Impurities, Impurities of Bivalirudin |
| CAT No. | CS-T-93587 |
| CAS No. | Not Available |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 2051.17 g/mol |
| Mol. For. | C₉₃H₁₃₁N₂₃O₃₀ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Bivalirudin |
| Purity | 95% |
| Smileys | H-D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Des-(Glu13)-Bivalirudin is a synthetic peptide that is used as an anticoagulant. It is a derivative of bivalirudin, a direct thrombin inhibitor that is commonly used during cardiac procedures such as angioplasty and stent placement. Des-(Glu13)-Bivalirudin has been modified to remove the glutamic acid residue at position 13, which enhances its pharmacological activity and prolongs its half-life in the body.
The chemical structure of des-(Glu13)-Bivalirudin consists of a chain of 20 amino acids, with a molecular weight of approximately 2180 Da. It selectively binds to the active site of thrombin, inhibiting its ability to form fibrin clots and preventing the formation of blood clots. This mechanism of action makes it an effective treatment option for preventing thrombus formation and reducing the risk of blood clots.
Des-(Glu13)-Bivalirudin is administered intravenously and is typically dosed based on the patient's weight and the type of procedure being performed. It has a rapid onset of action and a short half-life, which allows for quick reversal in the event of bleeding or other adverse effects.
In summary, des-(Glu13)-Bivalirudin is a potent anticoagulant that is used to prevent blood clots during cardiac procedures. Its chemical structure and mechanism of action make it a valuable tool in reducing the risk of thrombus formation and improving outcomes for patients undergoing invasive cardiac procedures.
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Related Compounds
Bivalirudin Impurity 1 | Bivalirudin 1-11 Fragment Trifluoroacetic Acid Salt | Bivalirudin β-ASPA 9 Analog Trifluoroacetic Acid Salt | Bivalirudin Plus-Gly Fragment | Bivalirudin Des-Gly Fragment Trifluoroacetic Acid Salt | Bivalirudin α-ASPA 9 Analog Trifluoroacetic Acid Salt | des-Glu13 Bivalirudin(Secondary Standards traceble to USP) | Bivalirudin Plus-Gly Fragment Trifluoroacetic Acid Salt | Bivalirudin Des-Gly Fragment | alfa-Asp9 | Bivalirudin 12-20 Fragment Trifluoroacetic Acid Sal | Bivalirudin Impurity 3 (Bivalirudin D-Asn Impurity) | D-Phe12 - bivalirudin | beta-Asp9 | Bivalirudin-(D-Phe-12) | bivalirudin [12-20] fragment | Bivalirudin Impurity ([β-Asp9]-Bivalirudin) |