Ezetimibe Didesfluro impurity

Product Name Ezetimibe Didesfluro impurity
Alternate Names Ezetimibe Impurities, Impurities of Ezetimibe
CAT No. CS-T-15984
CAS No. 302781-98-2
Category Impurities
Stock IN-Stock
Mol. Wt. 391.43 g/mol
Mol. For. C₂₄H₂₂FNO₃
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Ezetimibe
Therapeutic Anti-Hyperlipidemics
Smileys O[C@H](C1=CC=C(F)C=C1)CC[C@@H]2[C@@H](C3=CC=C(O)C=C3)N(C4=CC=CC=C4)C2=O
Canonical Smiles C1=CC=C(C=C1)N2C(C(C2=O)CCC(C3=CC=C(C=C3)F)O)C4=CC=C(C=C4)O
InchIKey YWZUFJFIXFJKBD-XPWALMASSA-N
Inchl InChI=1S/C24H22FNO3/c25-18-10-6-16(7-11-18)22(28)15-14-21-23(17-8-12-20(27)13-9-17)26(24(21)29)19-4-2-1-3-5-19/h1-13,21-23,27-28H,14-15H2/t21-,22+,23-/m1/s1
IUPAC (3R,4S)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one
Controlled No
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Ezetimibe is a medication used to lower blood cholesterol levels by reducing the absorption of cholesterol in the intestine. However, during the synthesis of Ezetimibe, a byproduct called Ezetimibe Didesfluro Impurity is formed, which needs to be removed from the final product. Ezetimibe Didesfluro Impurity, also known as 2-Amino-2-methyl-1-propanol-1,3-difluoro-4-(4-fluorophenyl)-5-oxo-1,5-dihydro-4H-pyrazolo[3,4-d]pyridazin-6-olate, is a chemical compound that is classified as an impurity. It is formed during the process of synthesis of Ezetimibe, and it is essential to remove it from the final product as it can affect the efficacy of the medication. Chemically, Ezetimibe Didesfluro Impurity contains a pyrazolopyridazine ring system, which is characteristic of the Ezetimibe molecule. However, it also contains a difluoro group and a fluoro group, which are not present in the parent compound. These additional groups can cause changes in the physical and chemical properties of the compound, which can affect its pharmacological activity. In conclusion, Ezetimibe Didesfluro Impurity is an unwanted byproduct formed during the synthesis of Ezetimibe. It is essential to remove this impurity from the final product to ensure the efficacy and safety of the medication.

Related Compounds

O-Fluorobenzene isomer of Ezetimibe | Ezetimibe tetrahydropyran analog | Ezetimibe 2-Fluoro Hydroxy impurity | Ezetimibe Diol Impurity | Ezetimibe Impurity 15 | Ezetimibe Impurity 17 | Ezetimibe Impurity 11 | Ezetimibe Impurity 18 | RSR Ezetimibe | Ezetimibe Lactam Cleaved Alcohol | Ezetimibe ring open impurity | Ezetimibe 2-Fluoro impurity | O-Fluoroaniline isomer of Ezetimibe | SSR-Ezetimibe | Ezetimibe Benzyl Diol Impurity | Benzyl Ezetimibe ether | Ezetimibe Impurity B | Ezetimibe (3S,4S,3'R)-Isomer | Ezetimibe O-trimethylsilyl O-benzyl Impurity | Ezetimibe Desfluoro impurity | Ezetimibe Impurity 1 ((3'S,3R,4S)-Desfluoro Ezetimibe) | Ezetimibe Impurity 25 | Ezetimibe (3R,4R,3'R)-Isomer | RRR-Ezetimibe+SSS-Ezetimibe (Diastereomer mixture) | Methyl 5-(4-Fluorophenyl)-(5S)-hydroxypentanoate | Ezetimibe Diacid | Ezetimibe Lactone Impurity | N-Nitroso Ezetimibe Impurity | m-Fluoroaniline isomer of Ezetimibe | Ezetimibe Ring-opening Dehydrate Impurity | Ezetimibe Trihydroxy Impurity | Ezetimibe Triol Impurity | Ezetimibe Impurity C | ent-Ezetimibe | Ezetimibe Benzyl Impurity (MBZT-2) | Ezetimibe Impurity 10 | Ezetimibe Deprotected Impurity | Ezetimibe impurity (3-[5-(4-Fluoro-phenyl)-5-(R)-hydroxy-pentanoyl]-4-(S)-phenyl-oxazolidin-2-one) | Benzylated Ezetimibe | Ezetimibe Related Impurity 7 | Ezetimibe Dides fluoro impurity | Ezetimibe Azetidinone Ring opened impurity |

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