Sofosbuvir L-alanitate (Mixture of Diasteriomers)

Product Name Sofosbuvir L-alanitate (Mixture of Diasteriomers)
Alternate Names Sofosbuvir Impurities, Impurities of Sofosbuvir
CAT No. CS-O-14752
CAS No. 1190308-01-0
Category Impurities
Stock IN-Stock
Mol. Wt. 529.45 g/mol
Mol. For. C₂₂H₂₉FN₃O₉P
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Sofosbuvir
Purity 95%
Therapeutic Antiretroviral / Anti-HIV
Smileys C[C@H](NP(OC1=CC=CC=C1)(OC[C@H]2O[C@@H](N(C(N3)=O)C=CC3=O)[C@](C)(F)[C@@H]2O)=O)C(OC(C)C)=O
Canonical Smiles CC(C)OC(=O)C(C)NP(=O)(OCC1C(C(C(O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3
Inchl InChI=1S/C22H29FN3O9P/c1-13(2)33-19(29)14(3)25-36(31,35-15-8-6-5-7-9-15)32-12-16-18(28)22(4,23)20(34-16)26-11-10-17(27)24-21(26)30/h5-11,13-14,16,18,20,28H,12H2,1-4H3,(H,25,31)(H,24,27,30)/t14-,16+,18+,20+,22+,36+/m0/s1
IUPAC propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
Controlled No
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Sofosbuvir L-alaninate (mixture of diastereomers) is a chemical compound used in the treatment of hepatitis C virus (HCV). It is a prodrug of sofosbuvir, which is a nucleotide analog inhibitor of HCV polymerase NS5B. Sofosbuvir L-alaninate (mixture of diastereomers) is converted into sofosbuvir in the liver, which then inhibits the replication of the HCV virus in the body. Sofosbuvir L-alaninate (mixture of diastereomers) is administered orally in the form of tablets. The recommended dosage is one tablet (400 mg) once a day, taken with or without food. The treatment duration and dosage may vary depending on the severity of the infection and other factors. The chemical name of Sofosbuvir L-alaninate (mixture of diastereomers) is (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl]methoxy-phenoxy-phosphoryl]amino]propanoic acid. Its molecular formula is C22H29FN3O9P and its molecular weight is 529.45 g/mol. Sofosbuvir L-alaninate (mixture of diastereomers) is generally well-tolerated, but may cause some side effects such as headache, fatigue, nausea, and diarrhea. It is not recommended for use in patients with severe renal impairment or end-stage renal disease. It may also interact with other medications, so it is important to inform your doctor about any other medications you are taking before starting this treatment.

Related Compounds

Sofosbuvir Degradation Impurity 1 | N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine-1-methylethyl ester | Sofosbuvir impurity 32 | L-Alanine Isopropyl Ester Hydrochloride | Sofosbuvir impurity 6 | Sofosbuvir Chloro Analogue | Sofosbuvir impurity 12 | Chloro Sofosbuvir Desphosphate | Sofosbuvir Impurity D | Sofosbuvir impurity 9 | Sofosbuvir Impurity 11 | Ethyl 2-(triphenylphosphoranylidene)propanoate | Sofosbuvir intermediate isomer Impurity | Sofosbuvir 3’,5’-Bis-(S)-phosphate | Sofosbuvir impurity 19 | O-Desphenyl Sofosbuvir | Sofosbuvir Impurity | Ethyl sofosbuvir | Chloro (R)-Phosphoryl Sofosbuvir | Sofosbuvir Des L-​Alanine | Isopropyl N-[chloro(phenoxy)phosphoryl]-L-alaninate | Sofosbuvir impurity 3 | Sofosbuvir impurity 43 | Sofosbuvir Dimer | Sofosbuvir D-Alaninate | Sofosbuvir impurity 5 |

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