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1-(3-Chlorophenyl)piperazine

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1-(3-Chlorophenyl)piperazine

Intermediate · API Family: Trazodone · CAT No. CS-T-12416 · CAS No. 6640-24-0
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For Research & Analytical Purposes. Not for Personal use.
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Packaging & Handling

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Documentation Available
Detailed specifications, certificates, and supporting documents are available upon request.
Storage: Refer MSDS for complete information.
Hazard: Refer MSDS for accurate information.

1-(3-Chlorophenyl)piperazine Product Information

1-(3-Chlorophenyl)piperazine is listed under Intermediate and is intended for analytical research, quality control and pharmaceutical reference standard applications. It is associated with Trazodone. The product is supplied by Clearsynth under CAT No. CS-T-12416.

Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight and product enquiry details.

Technical Data

Product Name
1-(3-Chlorophenyl)piperazine
CAS No.
6640-24-0
CAT No.
CS-T-12416
HSN Code
38229010
Country of Origin
Can be shipped from India, Canada and USA
Molecular Formula
C10H13ClN2
Molecular Weight
196.7
Category
API Family
Storage Condition
Refer MSDS for complete information.
Hazard Compound
Refer MSDS for accurate information.

Description

Regulatory Description
1-(3-Chlorophenyl)piperazine is supplied with detailed characterization data compliant with regulatory guideline. 1-(3-Chlorophenyl)piperazine can be used for analytical method development, method validation (AMV), Quality Control (QC) application for Abbreviated New Drug Application (ANDA), or during commercial production of Trazodone.
Overview
"It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone. The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone."
Synonyms
1-(3-Chlorophenyl)piperazine
Application Notes
"It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone. The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone."
References

Product Applications & Regulatory Search Terms

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