Product Detail
(-)-N-Deacetyl Colchicine
Colchicine Metabolite
Stock Status: In Stock
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For Research & Analytical Purposes. Not for Personal use.
Category
Metabolite
API Family
Colchicine
Storage
2-8°C
Hazard Information
Refer MSDS for accurate information.
(-)-N-Deacetyl Colchicine Product Information
(-)-N-Deacetyl Colchicine is listed under Metabolite. It is associated with Colchicine and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-T-14488.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight, stock enquiry details and supporting documentation.
Technical Data
Product Name
(-)-N-Deacetyl Colchicine
CAS No.
3476-50-4
CAT No.
CS-T-14488
Molecular Formula
C20H23NO5
Molecular Weight
357.4
Category
API Family
Storage Condition
2-8°C
SMILES
COC(C(OC)=C1OC)=CC2=C1C3=CC=C(OC)C(C=C3[C@@H](N)CC2)=O
IUPAC Name
"(S)-7-Amino-1,2,3,10-tetramethoxy-6,7-dihydrobenzo[a]heptalen-9(5H)-one"
Hazard Compound
Refer MSDS for accurate information.
Description
Overview
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
Synonyms
N-Deacetyl Colchicine
Application Notes
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
References
"Sharma, S,, et al,: Biochem,, 49, 2932 (2010), Bartusik, D,, et al,: Bioorg, Chem,, 38, 1 (2010), Passarella, D,, et al,: Eur, J, Med, Chem,, 45, 219 (2010),"
