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Tamoxifen

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Tamoxifen

API · API Family: Tamoxifen · CAT No. CS-T-43118 · CAS No. 10540-29-1
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For Research & Analytical Purposes. Not for Personal use.
Clearsynth product packaging

Packaging & Handling

Indicative product packaging is shown for visual reference. Actual packaging may vary based on pack size, quantity, storage condition and shipping requirements.

Documentation Available
Detailed specifications, certificates, and supporting documents are available upon request.
Storage: Refer MSDS for complete information.
Hazard: Refer MSDS for accurate information.

Tamoxifen Product Information

Tamoxifen is listed under API and is intended for analytical research, quality control and pharmaceutical reference standard applications. It is associated with Tamoxifen. The product is supplied by Clearsynth under CAT No. CS-T-43118.

Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight and product enquiry details.

Technical Data

Product Name
Tamoxifen
CAS No.
10540-29-1
CAT No.
CS-T-43118
HSN Code
38229010
Country of Origin
Can be shipped from India, Canada and USA
Molecular Formula
C26H29NO
Molecular Weight
371.51
Category
API Family
Storage Condition
Refer MSDS for complete information.
Hazard Compound
Refer MSDS for accurate information.

Description

Regulatory Description
Tamoxifen is supplied with detailed characterization data compliant with regulatory guideline. Tamoxifen can be used for analytical method development, method validation (AMV), Quality Control (QC) application for Abbreviated New Drug Application (ANDA), or during commercial production of Tamoxifen.
Overview
"Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells."
Synonyms
Tamoxifen
Application Notes
"Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells."
References

Product Applications & Regulatory Search Terms

Useful product, supplier and regulatory search terms for this reference standard.

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