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(R)-Sofosbuvir Pentafluorophenoxy Analogue
| Chemical Name | (R)-Sofosbuvir Pentafluorophenoxy Analogue |
|---|---|
| CAT No. | CS-O-11149 |
| CAS No. | 1334513-02-8 |
| Status | Available for Immediate Dispatch |
| Category | Impurities, Bulk Drug Intermediates |
| Mol. Wt. | 453.29 mol/g |
| Mol. For. | C18H17F5NO5P |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
Additional Information
| Packing | Product will be supplied in Vials, in certain conditions we also use 'Septa Vials' |
|---|---|
| Controlled | No |
| Parent API | Sofosbuvir |
| Purity | 99.57 |
| Therapeutic | Antiretroviral / Anti-HIV |
| Smileys | O=[P@@](OC1=CC=CC=C1)(N[C@H](C)C(OC(C)C)=O)OC(C(F)=C(F)C(F)=C2F)=C2F |
| Canonical Smiles | CC(C)OC(=O)C(C)NP(=O)(OC1=CC=CC=C1)OC2=C(C(=C(C(=C2F)F)F)F)F |
| InchIKey | MIILDBHEJQLACD-ZJPIPACBSA-N |
| Inchl | InChI=1S/C18H17F5NO5P/c1-9(2)27-18(25)10(3)24-30(26,28-11-7-5-4-6-8-11)29-17-15(22)13(20)12(19)14(21)16(17)23/h4-10H,1-3H3,(H,24,26)/t10-,30-/m0/s1 |
| IUPAC | propan-2-yl (2S)-2-[[(2,3,4,5,6-pentafluorophenoxy)-phenoxyphosphoryl]amino]propanoate |
| Hazardous | Yes |
Usage and description
(R)-Sofosbuvir Pentafluorophenoxy Analogue is a chemical compound that belongs to the class of antiviral agents known as nucleotide analogues. It is an isomer of Sofosbuvir, which is a widely used drug for the treatment of hepatitis C. This analogue has a pentafluorophenoxy group attached to its structure, which enhances its activity against the hepatitis C virus.
The usage of (R)-Sofosbuvir Pentafluorophenoxy Analogue is primarily for the treatment of hepatitis C virus infections. It is a prodrug that gets converted into its active form inside the liver cells. Once activated, it inhibits the replication of the hepatitis C virus by disrupting the synthesis of viral RNA. This process ultimately leads to the eradication of the virus from the patient's body.
Chemically, (R)-Sofosbuvir Pentafluorophenoxy Analogue is an organic compound with a molecular formula of C22H16F5N3O8P. Its molecular weight is 595.35 g/mol. The compound has a chiral center, and its stereochemistry is (R)-configuration. The pentafluorophenoxy group attached to the molecule enhances its lipophilicity, resulting in better absorption and distribution in the body.
In conclusion, (R)-Sofosbuvir Pentafluorophenoxy Analogue is a potent antiviral agent that is effective against hepatitis C virus infections. Its chemical structure and mechanism of action make it an essential drug in the treatment of this disease.
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