Amlodipine EP Impurity B

Product Name Amlodipine EP Impurity B
Alternate Names Amlodipine Impurities, Impurities of Amlodipine
CAT No. CS-O-07174
CAS No. 721958-72-1
Category Impurities
Stock IN-Stock
Mol. Wt. 570.03 g/mol
Mol. For. C₂₉H₃₂ClN₃O₇
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Amlodipine
Purity 95%
Therapeutic Anti-Hypertensives
Smileys O=C(C(C(C(C=CC=C1)=C1Cl)C(C(OC)=O)=C(C)N2)=C2COCCNC(C(C=CC=C3)=C3C(NC)=O)=O)OCC
Canonical Smiles CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCNC(=O)C3=CC=CC=C3C(=O)NC
InchIKey SNNCONCKJDOFKX-UHFFFAOYSA-N
Inchl InChI=1S/C29H32ClN3O7/c1-5-40-29(37)25-22(16-39-15-14-32-27(35)19-11-7-6-10-18(19)26(34)31-3)33-17(2)23(28(36)38-4)24(25)20-12-8-9-13-21(20)30/h6-13,24,33H,5,14-16H2,1-4H3,(H,31,34)(H,32,35)
IUPAC 5-O-ethyl 3-O-methyl 4-(2-chlorophenyl)-2-methyl-6-[2-[[2-(methylcarbamoyl)benzoyl]amino]ethoxymethyl]-1,4-dihydropyridine-3,5-dicarboxylate
Controlled No
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Amlodipine EP Impurity B is a chemical compound that is used in the pharmaceutical industry as a reference standard for the development and testing of drugs that contain Amlodipine. Amlodipine is a calcium channel blocker that is commonly used to treat hypertension, angina, and other cardiovascular diseases. The presence of impurities in Amlodipine can have adverse effects on the efficacy and safety of the drug, making the use of reference standards like Amlodipine EP Impurity B essential for ensuring the quality and purity of the final drug product. Chemically, Amlodipine EP Impurity B is known as (RS)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid dimethyl ester. It has a molecular weight of 444.95 g/mol and a melting point of 158-160°C. The compound is soluble in organic solvents like methanol and ethanol, but is insoluble in water. The use of Amlodipine EP Impurity B as a reference standard in drug development and testing ensures that the final drug product meets the required quality and purity standards. It enables pharmaceutical companies to accurately determine the concentration of impurities in Amlodipine and take appropriate measures to eliminate them.

Related Compounds

Amlodipine For Peak Identification | Phthaloyl Amlodipine Dimethyl Ester | Amlodipine EP Impurity E Maleate | N-Fomyl Amlodipine | Amlodipine Mannitol Adduct Acetate Salt | Amlodipine aminoethyl | Amlodipine Related Compound A | Amlodipine N-Galactose | Hydroxyethyl phthalyl amlodipine | R-Amlodipine Besilate | Amlodipine Impurity 8 | N-Nitroso Amlodipine | Amlodipine Impurity 19 | Atorvastatin-Amlodipine Adduct | Amlodipine EP Impurity F | N-Nitroso Amlodipine EP Impurity F | Amlodipine Aspartic Acid Impurity | Amlodipine Nitroso Impurity | Amlodipine EP Impurity H | Amlodipine Mannitol Adduct HCl Salt | Amlodipine orotate | Amlodipin EP Impurity D | Amlodipine EP Impurity D HCl | Amlodipine Impurity 29 | Amlodipine EP Impurity G | Amlodipine Galactose Adduct | Amlodipine Lactose adduct | Deschloro Amlodipine | Amlodipine Impurity 9 | Amlodipine Impurity | Amlodipine Methyl Ester | Dehydro Amlodipine N-Oxide | Amlodipine Impurity F Maleate | Amlodipine N-Lactoside | Desmethyl Amlodipine | Dimethoxy Impurity Deschloro Amlodipine | Amlodipine Azido Impurity | Amlodipine Impurity 34 | R-Amlodipine hemipentahydrate | Amlodipine EP Impurity D Oxalate Salt | Amlodipine Impurity 32 | Di-acid Amlodipine | Amlodipine Impurity 38 | Amlodipine EP Impurity E | Amlodipine EP Impurity C | Amlodipine morpholine impurity | Amlodipine EP Impurity A | Amlodipine Impurity 25 | Atorvastatin Amlodipine Dimer | Amlodipine Besylate Impurity D Besylate salt | Amlodipine Mannitol Adduct | Amlodipine Impurity 61 |

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