Desmethyl Amlodipine
| Product Name | Desmethyl Amlodipine |
|---|---|
| Alternate Names | Amlodipine Impurities, Impurities of Amlodipine |
| CAT No. | CS-O-14974 |
| CAS No. | 113994-37-9 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Amlodipine |
| Therapeutic | Anti-Hypertensives |
| Smileys | O=C(C(C(C(C=CC=C1)=C1Cl)C(C(O)=O)=C(C)N2)=C2COCCN)OCC |
| Canonical Smiles | CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)O)C)COCCN |
| InchIKey | RMMLXNROVBYURX-UHFFFAOYSA-N |
| Inchl | InChI=1S/C19H23ClN2O5/c1-3-27-19(25)17-14(10-26-9-8-21)22-11(2)15(18(23)24)16(17)12-6-4-5-7-13(12)20/h4-7,16,22H,3,8-10,21H2,1-2H3,(H,23,24) |
| IUPAC | 6-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-5-ethoxycarbonyl-2-methyl-1,4-dihydropyridine-3-carboxylic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Desmethyl Amlodipine is a chemical compound that is used in the treatment of hypertension, angina, and other cardiovascular disorders. It is a metabolite of Amlodipine, which is a calcium channel blocker that works by relaxing the smooth muscles of the blood vessels, thereby reducing the pressure and increasing blood flow.
Desmethyl Amlodipine is a white crystalline powder that is soluble in water and organic solvents. It is structurally similar to Amlodipine, but it lacks the dihydropyridine ring structure that is present in Amlodipine. This makes Desmethyl Amlodipine less potent than Amlodipine, but it still has significant antihypertensive effects.
The chemical formula of Desmethyl Amlodipine is C20H25ClN2O5, and its molecular weight is 414.88 g/mol. It is metabolized in the liver and excreted in the urine. The half-life of Desmethyl Amlodipine is approximately 30 hours, which is longer than Amlodipine.
Desmethyl Amlodipine is usually administered orally in the form of tablets. The recommended dosage for adults is usually 2.5 to 10 mg per day, depending on the severity of the condition being treated. It should not be used in patients with severe hepatic impairment or hypotension. Common side effects of Desmethyl Amlodipine include dizziness, headache, flushing, and edema.
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Related Compounds
Amlodipine orotate | Dehydro Amlodipine N-Oxide | Amlodipine Azido Impurity | Amlodipine EP Impurity G | N-Nitroso Amlodipine EP Impurity F | Amlodipine Impurity 9 | Amlodipine Impurity 61 | Amlodipine EP Impurity D HCl | Amlodipine Nitroso Impurity | Dimethoxy Impurity Deschloro Amlodipine | Amlodipine aminoethyl | Amlodipine EP Impurity B | Amlodipine N-Lactoside | Amlodipine EP Impurity E Maleate | Amlodipine Besylate Impurity D Besylate salt | Amlodipine N-Galactose | Amlodipine Impurity 29 | Amlodipine EP Impurity A | Amlodipine morpholine impurity | Amlodipine Impurity 34 | Amlodipine Impurity 19 | Amlodipine EP Impurity D Oxalate Salt | N-Nitroso Amlodipine | Amlodipine Lactose adduct | Amlodipine Mannitol Adduct Acetate Salt | Amlodipine Impurity | Deschloro Amlodipine | Amlodipine Mannitol Adduct | Amlodipin EP Impurity D | Amlodipine Related Compound A | Amlodipine EP Impurity H | Amlodipine EP Impurity E | N-Fomyl Amlodipine | Amlodipine EP Impurity C | Amlodipine EP Impurity F | Atorvastatin Amlodipine Dimer | Hydroxyethyl phthalyl amlodipine | Amlodipine Mannitol Adduct HCl Salt | Amlodipine Aspartic Acid Impurity | Phthaloyl Amlodipine Dimethyl Ester | R-Amlodipine hemipentahydrate | R-Amlodipine Besilate | Amlodipine Methyl Ester | Amlodipine Galactose Adduct | Atorvastatin-Amlodipine Adduct | Amlodipine Impurity F Maleate | Amlodipine Impurity 25 | Amlodipine Impurity 38 | Amlodipine For Peak Identification | Di-acid Amlodipine | Amlodipine Impurity 32 | Amlodipine Impurity 8 |