Desmethyl Amlodipine

Product Name Desmethyl Amlodipine
Alternate Names Amlodipine Impurities, Impurities of Amlodipine
CAT No. CS-O-14974
CAS No. 113994-37-9
Category Impurities
Stock IN-Stock
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Amlodipine
Therapeutic Anti-Hypertensives
Smileys O=C(C(C(C(C=CC=C1)=C1Cl)C(C(O)=O)=C(C)N2)=C2COCCN)OCC
Canonical Smiles CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)O)C)COCCN
Inchl InChI=1S/C19H23ClN2O5/c1-3-27-19(25)17-14(10-26-9-8-21)22-11(2)15(18(23)24)16(17)12-6-4-5-7-13(12)20/h4-7,16,22H,3,8-10,21H2,1-2H3,(H,23,24)
IUPAC 6-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-5-ethoxycarbonyl-2-methyl-1,4-dihydropyridine-3-carboxylic acid
Controlled No
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Desmethyl Amlodipine is a chemical compound that is used in the treatment of hypertension, angina, and other cardiovascular disorders. It is a metabolite of Amlodipine, which is a calcium channel blocker that works by relaxing the smooth muscles of the blood vessels, thereby reducing the pressure and increasing blood flow. Desmethyl Amlodipine is a white crystalline powder that is soluble in water and organic solvents. It is structurally similar to Amlodipine, but it lacks the dihydropyridine ring structure that is present in Amlodipine. This makes Desmethyl Amlodipine less potent than Amlodipine, but it still has significant antihypertensive effects. The chemical formula of Desmethyl Amlodipine is C20H25ClN2O5, and its molecular weight is 414.88 g/mol. It is metabolized in the liver and excreted in the urine. The half-life of Desmethyl Amlodipine is approximately 30 hours, which is longer than Amlodipine. Desmethyl Amlodipine is usually administered orally in the form of tablets. The recommended dosage for adults is usually 2.5 to 10 mg per day, depending on the severity of the condition being treated. It should not be used in patients with severe hepatic impairment or hypotension. Common side effects of Desmethyl Amlodipine include dizziness, headache, flushing, and edema.

Related Compounds

Amlodipin EP Impurity D | Amlodipine N-Galactose | Amlodipine EP Impurity C | Amlodipine EP Impurity D HCl | Amlodipine EP Impurity D Oxalate Salt | Amlodipine Impurity 29 | Amlodipine Impurity 8 | Amlodipine orotate | Dehydro Amlodipine N-Oxide | Amlodipine EP Impurity E | Amlodipine Impurity 9 | R-Amlodipine hemipentahydrate | Amlodipine Besylate Impurity D Besylate salt | Amlodipine Lactose adduct | Amlodipine EP Impurity A | Amlodipine Impurity 61 | N-Fomyl Amlodipine | Amlodipine Impurity | Amlodipine Impurity 19 | Atorvastatin Amlodipine Dimer | Atorvastatin-Amlodipine Adduct | R-Amlodipine Besilate | Amlodipine Impurity 38 | Di-acid Amlodipine | Amlodipine For Peak Identification | Amlodipine Methyl Ester | Amlodipine EP Impurity G | Amlodipine Mannitol Adduct HCl Salt | Amlodipine EP Impurity F | Amlodipine Aspartic Acid Impurity | Amlodipine Mannitol Adduct Acetate Salt | Amlodipine Impurity 32 | Amlodipine EP Impurity E Maleate | Amlodipine Related Compound A | Amlodipine Impurity F Maleate | Amlodipine Azido Impurity | Hydroxyethyl phthalyl amlodipine | Amlodipine Galactose Adduct | Amlodipine EP Impurity B | Phthaloyl Amlodipine Dimethyl Ester | Amlodipine aminoethyl | Amlodipine Impurity 25 | Amlodipine Mannitol Adduct | N-Nitroso Amlodipine EP Impurity F | Amlodipine Impurity 34 | Amlodipine morpholine impurity | Dimethoxy Impurity Deschloro Amlodipine | Amlodipine EP Impurity H | Amlodipine N-Lactoside | N-Nitroso Amlodipine | Deschloro Amlodipine | Amlodipine Nitroso Impurity |

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