Amlodipine N-Lactoside

Product Name Amlodipine N-Lactoside
Alternate Names Amlodipine Impurities, Impurities of Amlodipine
CAT No. CS-P-03120
CAS No. 749864-27-5
Category Impurities
Stock IN-Stock
Mol. Wt. 733.16 g/mol
Mol. For. C₃₂H₄₅ClN₂O₁₅
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Amlodipine
Purity 95%
Therapeutic Anti-Hypertensives
Smileys O=C(C1=C(COCCNC2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O[C@@H]3[C@@H]([C@H]([C@H]([C@@H](CO)O3)O)O)O)O)O)NC(C)=C(C(OC)=O)C1C4=CC=CC=C4Cl)OCC
Controlled No
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Amlodipine N-Lactoside is a chemical compound that belongs to the family of dihydropyridine calcium channel blockers. It has been developed as a prodrug of amlodipine, which is one of the most widely used antihypertensive drugs globally. Amlodipine N-Lactoside is used to treat hypertension, angina, and other cardiovascular diseases. The compound works by blocking the influx of calcium ions into the smooth muscle cells of the blood vessels, leading to vasodilation and a reduction in blood pressure. Amlodipine N-Lactoside has several advantages over amlodipine. It has better solubility and bioavailability, which means that it can be absorbed more efficiently by the body, and therefore, it requires a lower dose for therapeutic effect. Additionally, Amlodipine N-Lactoside has fewer side effects than amlodipine, such as headache, flushing, and edema. The chemical structure of Amlodipine N-Lactoside is a lactose conjugate of amlodipine, with the lactose moiety acting as a prodrug carrier. After oral administration, the lactose moiety is cleaved by enzymes in the intestine, releasing amlodipine into the bloodstream. This process leads to a slower and more prolonged release of amlodipine, resulting in a more stable and long-lasting therapeutic effect. In conclusion, Amlodipine N-Lactoside is a promising prodrug of amlodipine that offers better solubility, bioavailability, and fewer side effects. It has the potential to improve the treatment of hypertension and other cardiovascular diseases.

Related Compounds

Amlodipine Mannitol Adduct HCl Salt | Dimethoxy Impurity Deschloro Amlodipine | Amlodipine morpholine impurity | Amlodipine Impurity 32 | Amlodipine EP Impurity E | Amlodipine Impurity F Maleate | Amlodipine Nitroso Impurity | Amlodipine EP Impurity H | Amlodipine Methyl Ester | Amlodipin EP Impurity D | Amlodipine EP Impurity C | Atorvastatin Amlodipine Dimer | Deschloro Amlodipine | Amlodipine Mannitol Adduct Acetate Salt | Amlodipine Impurity | Amlodipine Galactose Adduct | Di-acid Amlodipine | Desmethyl Amlodipine | Amlodipine N-Galactose | Amlodipine EP Impurity D Oxalate Salt | Hydroxyethyl phthalyl amlodipine | Amlodipine Besylate Impurity D Besylate salt | Amlodipine Impurity 25 | Amlodipine EP Impurity F | Amlodipine Lactose adduct | Amlodipine Impurity 8 | Amlodipine EP Impurity D HCl | R-Amlodipine hemipentahydrate | N-Nitroso Amlodipine | Amlodipine EP Impurity B | Amlodipine Impurity 9 | N-Fomyl Amlodipine | Amlodipine Mannitol Adduct | Amlodipine Aspartic Acid Impurity | Amlodipine orotate | Amlodipine Impurity 29 | Phthaloyl Amlodipine Dimethyl Ester | Amlodipine Azido Impurity | Amlodipine EP Impurity A | Amlodipine Impurity 19 | Amlodipine Impurity 34 | Atorvastatin-Amlodipine Adduct | Amlodipine Related Compound A | R-Amlodipine Besilate | Amlodipine EP Impurity G | N-Nitroso Amlodipine EP Impurity F | Amlodipine aminoethyl | Amlodipine EP Impurity E Maleate | Dehydro Amlodipine N-Oxide | Amlodipine Impurity 38 | Amlodipine Impurity 61 | Amlodipine For Peak Identification |

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